SML1103

Entecavir

≥98% (HPLC), Nucleic acid synthesis inhibitor, powder

• Synonim(y): 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, 2-Amino-9-[(1S,3R,4S)-4-hydroxy-3-hydroxymethyl-2-methylene-cyclopentyl]-3,9-dihydro-purin-6-one, BMS 200475, SQ 34,676
• Wzór empiryczny (zapis Hilla): C₁₂H₁₅N₅O₃
• Numer CAS: 142217-69-4
• Masa cząsteczkowa: 277.28
• UNSPSC Code: 51111800
• PubChem Substance ID: 329825478
• NACRES: NA.77
• MDL number: MFCD11046562
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Właściwości

• Nazwa produktu: Entecavir, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D +25 to +40°, c = 0.2 in H₂O
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 0.5 mg/mL, clear (warmed)
• storage temp.: −20°C
• SMILES string: O=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)C3=C)C=N2)NC(N)=N1
• InChI: 1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8-/m0/s1
• InChI key: QDGZDCVAUDNJFG-FXQIFTODSA-N

Opis

Biochem/physiol Actions

Entecavir is an antiviral guanine analog that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir is used to treat hepatitis B.

Entecavir is an antiviral guanine analog that inhibits reverse transcription, DNA replication and transcription.

Entecavir is used as an effective drug to treat lamivudine-refractory patients with chronic hepatitis B virus (CHB) at a dose of 1 mg daily.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H351
• pcodes: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable