SML0784

BMS-303141

≥98% (HPLC), ATP citrate lyase inhibitor, powder

• Synonim(y): 3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1′-biphenyl]-3-yl)-benzenesulfonamide
• Wzór empiryczny (zapis Hilla): C₁₉H₁₅Cl₂NO₄S
• Numer CAS: 943962-47-8
• Masa cząsteczkowa: 424.30
• NACRES: NA.77
• UNSPSC Code: 51111800
• MDL number: MFCD25976797
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Nazwa produktu: BMS-303141, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=S(NC1=C(OC)C=CC(C2=CC=CC=C2)=C1)(C3=C(O)C(Cl)=CC(Cl)=C3)=O
• InChI: 1S/C19H15Cl2NO4S/c1-26-17-8-7-13(12-5-3-2-4-6-12)9-16(17)22-27(24,25)18-11-14(20)10-15(21)19(18)23/h2-11,22-23H,1H3
• InChI key: SIIPNDKXZOTLEA-UHFFFAOYSA-N

Opis

Application

BMS-303141 has been used for inhibition of ATP citrate lyase in breast cancer cell lines.

Biochem/physiol Actions

BMS-303141 is a potent inhibitor of ATP citrate lyase (ACL).

BMS-303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC₅₀ of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• hcodes: H413
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable