SML0597

Daurisoline

≥98% (HPLC)

• Synonim(y): (-)-Daurisoline, (1R)-1,2,3,4-Tetrahydro-1-[[4-hydroxy-3-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenyl]methyl]-6-methoxy-2-methyl-7-isoquinolinol, (R,R)-Daurisoline, O7-Demethyldauricine
• Wzór empiryczny (zapis Hilla): C₃₇H₄₂N₂O₆
• Numer CAS: 70553-76-3
• Masa cząsteczkowa: 610.74
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 15 mg/mL, clear
• storage temp.: −20°C
• SMILES string: N1([C@@H](c6c(cc(c(c6)OC)OC)CC1)Cc2ccc(cc2)Oc3c(ccc(c3)C[C@H]4N(CCc5c4cc(c(c5)OC)O)C)O)C
• InChI: 1S/C37H42N2O6/c1-38-15-13-26-20-36(43-4)37(44-5)22-29(26)30(38)16-23-6-9-27(10-7-23)45-35-18-24(8-11-32(35)40)17-31-28-21-33(41)34(42-3)19-25(28)12-14-39(31)2/h6-11,18-22,30-31,40-41H,12-17H2,1-5H3/t30-,31-/m1/s1
• InChI key: BURJAQFYNVMZDV-FIRIVFDPSA-N

Opis

Biochem/physiol Actions

Daurisoline alkaloid isolated from the rhizomes of Menispermum dauricum that exhibit varies pharmacological activities including antiplatelet aggregation, anti-inflammatory, neuron-protective properties, and antiarrhythmic effect. It appears that antiarrhythmic effect of daurisoline is maintained through blockade of hERG channels.

Daurisoline is antiarrythmic, anti-inflammatory, neuron-protective; and blocks hERG channels.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable