SML0397

DR2313

≥98% (HPLC)

• Synonim(y): 3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one
• Wzór empiryczny (zapis Hilla): C₈H₁₀N₂OS
• Numer CAS: 284028-90-6
• Masa cząsteczkowa: 182.24
• NACRES: NA.77
• PubChem Substance ID: 329825393
• UNSPSC Code: 12352200
• MDL number: MFCD08703132
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: >2 mg/mL (warmed)
• storage temp.: 2-8°C
• SMILES string: CC1=NC(=O)C2=C(CCSC2)N1
• InChI: 1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11)
• InChI key: HRYKZAKEAVZGJD-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

DR2313 is a PARP inhibitor.

DR2313 is a PARP-1; PARP-2 inhibitor (Ki = 0.23 mM). DR2313 has neuroprotective effects in both in vivo and in vitro ischemic models, and reduces cortical infarct volume in focal ischemia in rats.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable