SCP0002

Acetyl-Amyloid β 25-35

• Wzór empiryczny (zapis Hilla): C₄₇H₈₃N₁₃O₁₅S₁
• Masa cząsteczkowa: 1102.31
• NACRES: NA.32
• UNSPSC Code: 12352202

Właściwości

• assay: ≥95% (HPLC)
• form: lyophilized
• composition: Peptide Content, ≥70%
• storage condition: protect from light
• UniProt accession no.: P05067
• storage temp.: −20°C
• Gene Information: human ... APP(351)

Opis

General description

Amyloid-β (Aβ) peptides are a major component of the senile plaques characteristic of the Alzheimer brain. It is a type- I transmembrane protein. The amyloid β precursor protein is cleaved to amyloid peptides 36-43 amino acids in length. Aβ (25-35) represents the region that aggregates during plaque formation and is a functional domain implicated in both neurotrophic and neurotoxic effects. The gene encoding amyloid-β is localized on human chromosome 21. Acetylation may improve stability in in vitro and in vivo assays.

Application

Acetyl-Amyloid β 25-35 has been used to prepare rat models with Alzheimer′s disease.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable