SAB5701724

Anti-Phospho-CDK1-Y15 antibody produced in rabbit

• Kod UNSPSC: 12352203
• NACRES: NA.43

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Postać: liquid
• reaktywność gatunkowa: rat, human, mouse
• stężenie: 0.43 mg/mL
• metody: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• numer dostępu UniProt: P06493
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: phosphorylation (pTyr15)
• informacje o genach: human ... CDK1(983)

Opis

Opis ogólny

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around Y15 of human CDK1 (NP_001777.1).

Postać fizyczna

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable