SAB4200734

Anti-IL6 high affinity antibody, Mouse monoclonal

clone IL6-2A3, purified from hybridoma cell culture

• Synonim(y): Anti-B-cell stimulatory factor 2 (BSF-2), Anti-CTL differentiation factor (CDF), Anti-Hybridoma growth factor, Anti-Interferon beta-2 (IFN-beta-2), Anti-Interleukin-6
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 200
• forma przeciwciała: purified from hybridoma cell culture
• rodzaj przeciwciała: primary antibodies
• klon: IL6-2A3, monoclonal
• Postać: buffered aqueous solution
• reaktywność gatunkowa: human
• stężenie: ~1.0 mg/mL
• metody: ELISA: suitable; immunoblotting: 0.125-0.25 μg/mL using recombinant human IL6 expressed in HEK-293T cells; immunoprecipitation (IP): 10-20 μg/test using concentrated supernatant of human osteosarcoma MG-63 cells treated with IL1β
• izotyp: IgG2a
• numer dostępu UniProt: P05231
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... IL6(3569)

Opis

Opis ogólny

Interleukin-6 (IL6) is a multifunctional cytokine.

Immunogen

recombinant human IL6

Zastosowanie

Anti-IL6 high affinity antibody, Mouse monoclonal has been used in

• immunoblotting
• immunoprecipitation
• ELISA

Działania biochem./fizjol.

Interleukin-6 (IL6) plays a wide variety of important biological roles in the immune, nervous and endocrine system. It is an essential component for hybridoma growth and is found in many supplemental cloning media. IL6 regulates acute and chronic inflammatory diseases and has been proven to be an excellent target for clinical treatment against autoimmune disorders such as rheumatoid arthritis, juvenile idiopathic arthritis and Castleman′s disease. IL6 also plays a key role in the pathogenesis of multiple myeloma.

Postać fizyczna

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable