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S7023

Sigma-Aldrich

Sera human

frozen liquid

Synonim(y):

Surowica krwi ludzkiej, Surowica ludzka

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50 ML
861,00 zł
100 ML
2370,00 zł

861,00 zł


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50 ML
861,00 zł
100 ML
2370,00 zł

About This Item

Kod UNSPSC:
12352207
NACRES:
NA.71

861,00 zł


Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności

pochodzenie biologiczne

human

Poziom jakości

Formularz

frozen liquid

pochodzenie

USA origin

Warunki transportu

dry ice

temp. przechowywania

−20°C

Opis ogólny

The serum is the fluid from plasma devoid of fibrinogen, prothrombin, and other clotting factors. It contains various plasma proteins, amino acids, polypeptides, growth factors, fat, carbohydrates, nucleic acid derivatives, hormones, inorganic minerals, and vitamins.

Zastosowanie

Sera human has been used:
  • to prepare the antigen standards for the validation assay of multiple-biomarker detection
  • as a quality check (QC) sample to optimize the experimental workflow
  • as a control in immunoproteomics assay

Działania biochem./fizjol.

Human serum is used as a cell culture supplement. It maintains physiological balance by stimulating or inhibiting cell growth. It is known to have an inhibitory action on endogenous and exogenous enzymes.

Oświadczenie o zrzeczeniu się odpowiedzialności

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


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Certyfikaty analizy (CoA)

Lot/Batch Number

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Rhys A Dunstan et al.
Microbiology spectrum, 9(1), e0102321-e0102321 (2021-08-26)
The production of capsular polysaccharides by Klebsiella pneumoniae protects the bacterial cell from harmful environmental factors such as antimicrobial compounds and infection by bacteriophages (phages). To bypass this protective barrier, some phages encode polysaccharide-degrading enzymes referred to as depolymerases to
Francesca L Short et al.
Infection and immunity, 88(8) (2020-06-10)
The serum complement system is a first line of defense against bacterial invaders. Resistance to killing by serum enhances the capacity of Klebsiella pneumoniae to cause infection, but it is an incompletely understood virulence trait. Identifying and characterizing the factors
Kuiama Lewandowski et al.
The Journal of molecular diagnostics : JMD, 19(2), 303-312 (2017-01-04)
Extraction of viral RNA and the storage of sample material are extremely important factors in the detection and whole genome sequencing (WGS) of viral pathogens. Although PCR-based detection methods focus on small amplicons, viral WGS applications require RNA of high
Josep Villanueva et al.
Nature protocols, 1(2), 880-891 (2007-04-05)
Blood is a convenient source of biomarkers. Readily obtainable, it immerses most tissues in the body and is therefore likely to contain cell-derived proteins and peptides that may provide information about various biological processes. Serum proteome and peptidome profiling--using mass
Sílvia A Sousa et al.
Vaccines, 8(3) (2020-09-10)
Infections by the Burkholderia cepacia complex (Bcc) remain seriously life threatening to cystic fibrosis (CF) patients, and no effective eradication is available. A vaccine to protect patients against Bcc infections is a highly attractive therapeutic option, but none is available.

Questions

  1. Could you provide more details about the processing method used to prepare frozen human serum? Specifically, how are the sera collected, pooled, and processed from whole blood? Additionally, I'm interested in learning about any quality control (QC) testing conducted beyond testing for infectious agents.

    1 answer
    1. The Technical Service department has collected historical data from various sources on the sera supplied to us from licensed donor centers in the United States. The sera, pooled from multiple normal subjects, is collected from clotted whole blood without additives and is "off the clot" with no azide added. The human serum undergoes testing for HIV and HBSAG by FDA-licensed labs. The donor pools can consist of up to 200 donors and are sterile filtered through a 0.22 micron filter. The product is not manufactured under GMP and is intended for laboratory or research use only. It is produced under ISO 9001 and undergoes sterility testing according to USP guidelines. For more information on the quality, please refer to the provided link.

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