S2812

SNC80

≥98% (HPLC), δ opioid receptor agonist, solid

• Synonim(y): (+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide, SNC 80, SNC-80
• Wzór empiryczny (zapis Hilla): C₂₈H₃₉N₃O₂
• Numer CAS: 156727-74-1
• Masa cząsteczkowa: 449.63
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278698
• NACRES: NA.77
• MDL number: MFCD00672673
• Assay: ≥98% (HPLC)
• Form: solid

Właściwości

• Nazwa produktu: SNC80, ≥98% (HPLC), solid
• assay: ≥98% (HPLC)
• form: solid
• color: off-white
• solubility: DMSO: soluble
• SMILES string: CCN(CC)C(=O)c1ccc(cc1)[C@H](N2C[C@H](C)N(CC=C)C[C@H]2C)c3cccc(OC)c3
• InChI: 1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27?/m0/s1
• InChI key: KQWVAUSXZDRQPZ-QNWUEUMSSA-N
• Gene Information: human ... OPRD1(4985) ; mouse ... Oprd1(18386) ; rat ... Oprd1(24613), Oprm1(25601)

Opis

Application

Rats were administered SNC80 to study the role of nitric oxide synthase in peripheral antinociception mechanism.⁵

Biochem/physiol Actions

SNC80 is a δ opioid receptor agonist.

SNC80 is a highly selective agonist of δ opioid receptor but also binds to μ-δ opioid receptor heteromers to produce antinociception in mice.² It also acts as anti-depressant³, elicits dopamine-related behaviors and enhances behavioral responses to psychostimulants.⁴

Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)