R137

Ro 31-0432

solid

• Synonim(y): 3-(8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)-4-(1-methylindol-3-yl)maleimide hydrochloride, 3-[8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione monohydrochloride, Bisindoylmaleimide XI
• Wzór empiryczny (zapis Hilla): C₂₈H₂₈N₄O₂ · HCl
• Numer CAS: 145333-02-4
• Masa cząsteczkowa: 489.01
• UNSPSC Code: 12352200
• PubChem Substance ID: 329824001
• NACRES: NA.77
• Assay: ≥98% (TLC)
• Form: solid
• Storage condition: protect from light

Właściwości

• biological source: synthetic (organic)
• assay: ≥98% (TLC)
• form: solid
• storage condition: protect from light
• color: orange
• solubility: DMSO: 5 mg/mL, H₂O: insoluble
• storage temp.: −20°C
• SMILES string: Cl.CN(C)CC1CCn2c(C1)c(C3=C(C(=O)NC3=O)c4cn(C)c5ccccc45)c6ccccc26
• InChI: 1S/C28H28N4O2.ClH/c1-30(2)15-17-12-13-32-22-11-7-5-9-19(22)24(23(32)14-17)26-25(27(33)29-28(26)34)20-16-31(3)21-10-6-4-8-18(20)21;/h4-11,16-17H,12-15H2,1-3H3,(H,29,33,34);1H
• InChI key: HSPRASOZRZDELU-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

Protein kinase C (PKC) inhibitor; membrane-derived PKC inhibitor.

Features and Benefits

This compound is featured on the GRKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)