P5069

Prostaglandin F_2α tris salt

synthetic, suitable for cell culture

• Synonim(y): (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt, PGF_2α−Tris
• Wzór empiryczny (zapis Hilla): C₂₀H₃₄O₅ · C₄H₁₁NO₃
• Numer CAS: 38562-01-5
• Masa cząsteczkowa: 475.62
• UNSPSC Code: 12352209
• NACRES: NA.77
• PubChem Substance ID: 24898587
• EC Number: 254-002-3
• Beilstein/REAXYS Number: 4087514
• MDL number: MFCD00077863
• Biological source: synthetic
• Form: powder
• Assay: ≥99%

Właściwości

• Quality Level: 200
• biological source: synthetic
• assay: ≥99%
• form: powder
• technique(s): cell culture | mammalian: suitable
• solubility: ethanol: 50 mg/mL, clear, colorless
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: NC(CO)(CO)CO.[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])\C=C\[C@@H](O)CCCCC
• InChI: 1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1
• InChI key: IYGXEHDCSOYNKY-RZHHZEQLSA-N
• Gene Information: human ... PTGFR(5737)

Opis

Biochem/physiol Actions

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F_2α and luteal oxytocin is responsible for completion of luteolysis.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.

Prostaglandin F2α is induced by uterine-produced oxytocin and acts on the corpus luteum to cause luteolysis and inhibit progesterone production.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H360FD
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1B
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges