P2110

Anti-Platelet-Derived Growth Factor Receptor α antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonim(y): Anti-PDGF Rα
• UNSPSC Code: 51111800
• NACRES: NA.41
• MDL number: MFCD03444647
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA (d), IHC (p), Neutral, WB
• Citations: 5

Właściwości

• biological source: goat
• Quality Segment: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): direct ELISA: 0.5-1.0 μg/mL, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 15 μg/mL using human tissue sections, neutralization: suitable, western blot: 0.1-0.2 μg/mL
• UniProt accession no.: P16234
• storage temp.: −20°C
• Gene Information: human ... PDGFRA(5156)

Opis

General description

Blocks cell surface human or mouse PDGF Receptor α mediated biological activity induced by PDGF-AA.

Immunogen

recombinant soluble human platelet-derived growth factor receptor α expressed in Sf 21 cells.

Biochem/physiol Actions

Platelet-derived growth factor (PDGF) is a serum growth factor purified from human platelets. The cellular effects of PDGF are mediated by binding to PDGF α- and PDGF β-receptors which leads to activation of downstream signaling via PI3K, STAT and Ras/MAPK. PDGFR stimulates the proliferation of cells of connective tissue and glial cells, survival, differentiation, chemotaxis and wound healing.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 13 - Non Combustible Solids
• Co się dzieje?: WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable