P1761

trans-2-Phenylcyclopropylamine hemisulfate salt

• Synonim(y): Tranylcypromine
• Wzór liniowy: C₉H₁₁N · 1/2H₂SO₄
• Numer CAS: 13492-01-8
• Masa cząsteczkowa: 182.23
• NACRES: NA.77
• PubChem Substance ID: 329820106
• UNSPSC Code: 12352116
• EC Number: 236-807-1
• MDL number: MFCD00079222

Właściwości

• assay: ≥98% (perchloric acid titration)
• Quality Segment: 200
• form: powder
• solubility: water: 0.0333 g/mL, clear to slightly hazy, colorless to faintly yellow
• storage temp.: 2-8°C
• SMILES string: OS(O)(=O)=O.N[C@H]1C[C@@H]1c2ccccc2.N[C@H]3C[C@@H]3c4ccccc4
• InChI: 1S/2C9H11N.H2O4S/c2*10-9-6-8(9)7-4-2-1-3-5-7;1-5(2,3)4/h2*1-5,8-9H,6,10H2;(H2,1,2,3,4)/t2*8-,9+;/m11./s1
• InChI key: BKPRVQDIOGQWTG-KAVFMPKWSA-N

Opis

Biochem/physiol Actions

trans-2-Phenylcyclopropylamine acts as an inhibitor of lysine-specific demethylase 1 (LSD1). It exhibits anti-depressant and anxiolytic activity. Tranylcypromine shows therapeutic effects against mood and anxiety issues. It also exhibits anti-osteoclastogenic effects through monoamine oxidase-A (MAO-A). Tranylcypromine may play a role in bone remodeling in mice.

Non-selective MAO-A/B inhibitor.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06
• signalword: Danger
• hcodes: H300,H311 + H331
• pcodes: P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation
• Klasa składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges