N9412

6β-Naltrexol hydrate

≥96% (HPLC), powder

• Synonim(y): (5α,6β)-17-(Cyclopropylmethyl)-4,5-epoxy-morphinan-3,6,14-triol hydrate
• Wzór empiryczny (zapis Hilla): C₂₀H₂₅NO₄ · xH₂O
• Numer CAS: 1034528-53-4
• Masa cząsteczkowa: 343.42 (anhydrous basis)
• NACRES: NA.77
• PubChem Substance ID: 24724560
• UNSPSC Code: 12352200
• MDL number: MFCD08277038
• Assay: ≥96% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥96% (HPLC)
• form: powder
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• color: white
• solubility: DMSO: ~12 mg/mL, H₂O: insoluble
• storage temp.: 2-8°C
• SMILES string: [H]O[H].O[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC6CC6)c45
• InChI: 1S/C20H25NO4.H2O/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,14-15,18,22-24H,1-2,5-10H2;1H2/t14-,15-,18+,19+,20-;/m1./s1
• InChI key: VHGGWFVHXKTOPK-CDHBEYIESA-N

Opis

Biochem/physiol Actions

Neutral antagonist of the μ-opioid receptor. A reduction of withdrawal effects associated with neutral μ-opioid receptor antagonists may offer advantages in treating opioid overdose and addiction.

Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)