N3143

Nalidixic acid sodium salt

powder

• Synonim(y): 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt
• Wzór empiryczny (zapis Hilla): C₁₂H₁₁N₂NaO₃
• Numer CAS: 3374-05-8
• Masa cząsteczkowa: 254.22
• EC Number: 222-159-7
• UNSPSC Code: 12352200
• PubChem Substance ID: 329818602
• Beilstein/REAXYS Number: 3580062
• MDL number: MFCD00064376
• Form: powder

Właściwości

• sterility: γ-irradiated
• form: powder
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• mode of action: DNA synthesis | interferes, enzyme | inhibits
• SMILES string: [Na+].CCN1C=C(C([O-])=O)C(=O)c2ccc(C)nc12
• InChI: 1S/C12H12N2O3.Na/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;/h4-6H,3H2,1-2H3,(H,16,17);/q;+1/p-1
• InChI key: ROKRAUFZFDQWLE-UHFFFAOYSA-M

Opis

General description

Chemical structure: quinolone

Application

Recommended for use in molecular biology applications at 15 μg/ml

Biochem/physiol Actions

Nalidixic acid sodium salt is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae.

Preparation Note

Prepare stock solutions directly in the vial with sterile water (5-50 mg/ml). Stock solutions should be stored at −20 °C.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H317,H334,H361fd
• pcodes: P202 - P261 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves