N3139

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate

powder, BioReagent, suitable for cell culture

• Synonim(y): Triphosphopyridine nucleotide sodium salt hydrate
• Wzór empiryczny (zapis Hilla): C₂₁H₂₇N₇NaO₁₇P₃ · xH₂O
• Numer CAS: 698999-85-8
• Masa cząsteczkowa: 765.39 (anhydrous basis)
• NACRES: NA.75
• PubChem Substance ID: 24897624
• UNSPSC Code: 12352205
• MDL number: MFCD00150480
• Form: powder
• Assay: ≥98% (HPLC), ≥98% (spectrophotometric assay)
• Solubility: H₂O: 50 mg/mL

Właściwości

• product line: BioReagent
• Quality Segment: 200
• assay: ≥98% (HPLC), ≥98% (spectrophotometric assay)
• form: powder
• technique(s): cell culture | mammalian: suitable
• mp: 175-178 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL
• storage temp.: −20°C
• SMILES string: O[C@H]1[C@@H](O)[C@H]([N+]2=CC(C(N)=O)=CC=C2)O[C@@H]1COP(OP(OC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](OP(O)(O)=O)[C@@H]3O)([O-])=O)([O-])=O.O.[Na+]
• InChI: 1S/C21H28N7O17P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;;/m1../s1
• InChI key: CYQLUFJYVTUUFN-WUEGHLCSSA-M

Opis

Application

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate has been used in the purification and crystallization of CHORD–Sgt1 cytochrome b 5 reductases (CS–b5R). It has also been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM)/F-12 medium for direct hepatic reprogramming using mouse embryonic fibroblasts (MEFs).

Biochem/physiol Actions

Electron acceptor

Nicotinamide adenine dinucleotide phosphate (NADP) is an indispensable cofactor that participates in cellular redox reactions. It acts as a hydride-accepting coenzyme and participates in substrate oxidation reactions during metabolism.

Packaging

Packaged by solid weight.

Analysis Note

Meets or exceeds NRC specifications and is comparable to any commercial preparation available.

Other Notes

This is the common form of NADP. Do not confuse with 3′−NADP or α-NADP.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H319
• Ostrzeżenia: P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable