MAK261

Glycine Assay Kit (Fluorometric)

sufficient for 100 fluorometric tests

• Synonim(y): Fluorometric Glycine Detection Kit
• NACRES: NA.84
• UNSPSC Code: 12161503

Właściwości

• detection method: fluorometric
• relevant disease(s): cancer; neurological disorders
• storage temp.: −20°C

Opis

General description

Glycine (GLY) is a non-essential amino acid used to help create muscle tissue and convert glucose into energy. It′s basic functions include the participation in the synthesis of creatine, glutathione, heme groups, and conjugated bile acids (bile salts). It is also used in the synthesis of DNA and RNA. It is one of the most abundant residues in the triple-helical structure of collagen, which contributes to the elasticity of skin and connective tissue. It acts as a glucogenic amino acid regulating blood sugar levels. Glycine is necessary for central nervous system function. It possesses both inhibitory and excitatory neurotransmitter functions in the brain stem and spinal cord. Recent studies suggest, glycine may play a role in tumorigenesis and malignancy. Some of the external sources of glycine includes legumes, meat, fish and dairy products.

Application

Suitable for the detection of glycine in biological fluids such as serum, plasma, saliva, urine, etc

Biochem/physiol Actions

The Glycine Assay Kit is a simple and reliable, high throughput assay that detects the physiological concentration of glycine in a variety of biological fluids. In the assay, glycine is oxidized generating a fluorometric (lex = 535 nm/ lem = 587 nm) product, proportional to the glycine present. The assay is specific, and other standard and non-standard amino acids do not interfere with the assay. The kit is sensitive to 1 mM of glycine.

Features and Benefits

Compatible with high-throughput handling systems.

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Informacja o środkach bezpieczeństwa

• signalword: Danger
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• wgk: WGK 3
• pictograms: GHS08,GHS05,GHS09
• hcodes: H290,H334,H411,EUH430
• pcodes: P201 - P202 - P273 - P391 - P405 - P501
• Hazard Classifications: Aquatic Chronic 2 - ED ENV 1 - Met. Corr. 1 - Resp. Sens. 1
• Klasa składowania: 10 - Combustible liquids