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L9634

Sigma-Aldrich

Laminarin from Laminaria digitata

polysaccharide substrate for laminarinase

Synonim(y):

Laminaran

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100 MG
322,00 zł
500 MG
1190,00 zł
1 G
1840,00 zł
5 G
6250,00 zł

322,00 zł

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Wszystkie zdjęcia(5)

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100 MG
322,00 zł
500 MG
1190,00 zł
1 G
1840,00 zł
5 G
6250,00 zł

About This Item

Numer CAS:
9008-22-4
Numer WE:
232-712-4
Numer MDL:
MFCD00466918
Kod UNSPSC:
12352201
Identyfikator substancji w PubChem:
329817672
NACRES:
NA.25

322,00 zł

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pochodzenie biologiczne

algae (Laminaria digitata)

Formularz

powder

aktywność optyczna

[α]20/D -20 to -5 °, c = 4% (w/v) in water

kolor

beige

przydatny zakres pH

5

rozpuszczalność

water: 10 mg/mL, clear to slightly hazy, colorless to light yellow

temp. przechowywania

room temp

ciąg SMILES

O1[C@@H]([C@H]([C@@H]([C@H](C1O[C@H]3[C@@H]([C@H](OC([C@@H]3O)O)CO)O)O)OC2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)O)CO

InChI

1S/C18H32O16/c19-1-4-7(22)10(25)11(26)17(31-4)34-15-9(24)6(3-21)32-18(13(15)28)33-14-8(23)5(2-20)30-16(29)12(14)27/h4-29H,1-3H2/t4-,5-,6-,7-,8-,9-,10+,11-,12-,13-,14+,15+,16?,17?,18?/m1/s1

Klucz InChI

DBTMGCOVALSLOR-VPNXCSTESA-N

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Opis ogólny

The fronds of Laminaria and Saccharina species contain laminarin, a low molecular weight[1] storage glucan. It is localized to the vacuoles.[2] Laminarin structure contains β-(1,6)-intrachain linked (1,3)-β-d-glucan.[1]

Zastosowanie

Laminarin from Laminaria digitata has been used:
  • as a stimulant to study its effect on the respiratory burst using haemocytes of P. vannamei[3]
  • as a carbon source to study its effect on enzyme production using Pichia membranifaciens culture[4]
  • as a carbon source for Polaribacter sp. culture[5]

Działania biochem./fizjol.

Laminarin is a biologically active compound effective against inflammation. It serves as an antioxidant and anticoagulant. Laminarin also inhibits apoptosis and tumor development.[1] It acts as a predominant source of carbon among aquatic prokaryotes.[2]
Laminarin is a polysaccharide of glucose found in brown algae and utilized as a food reserve.

Inne uwagi

Polysaccharide; primarily poly(β-Glc-[1→3]) with some β-(1→6) interstrand linkages and branch points.
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Substraty

Substrate for laminarinase.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number
0000439287
0000439286
0000439285
0000439285
0000439287

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Jeśli potrzebujesz konkretnej wersji, możesz wyszukać konkretny certyfikat według numeru partii lub serii.

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USP

USP

1048288

Beta glukan

Mannan from Saccharomyces cerevisiae prepared by alkaline extraction

Sigma-Aldrich

M7504

Mannan from Saccharomyces cerevisiae

β-D-Glucan from barley for use with Total Dietary Fiber Control Kit, TDF-C10

Supelco

G7391

β-D-Glucan from barley

Niches of two polysaccharide-degrading Polaribacter isolates from the North Sea during a spring diatom bloom
Xing P, et al.
The ISME Journal, 9(6), 1410-1410 (2015)
Tomasz Lipinski et al.
Journal of immunology (Baltimore, Md. : 1950), 190(8), 4116-4128 (2013-03-22)
In a previous attempt to generate a protective vaccine against Candida albicans, a β-mannan tetanus toxoid conjugate showed poor immunogenicity in mice. To improve the specific activation toward the fungal pathogen, we aimed to target Dectin-1, a pattern-recognition receptor expressed
Manuel Martinez-Garcia et al.
PloS one, 7(4), e35314-e35314 (2012-04-27)
Microbial hydrolysis of polysaccharides is critical to ecosystem functioning and is of great interest in diverse biotechnological applications, such as biofuel production and bioremediation. Here we demonstrate the use of a new, efficient approach to recover genomes of active polysaccharide
Michael H Huesemann et al.
Bioresource technology, 108, 305-309 (2012-01-27)
The objective of this study was to subject mannitol, either as a sole carbon source or in combination with glucose, and aqueous extracts of the kelp Saccharina spp., containing mannitol and laminarin, to acetone-butanol fermentation by Clostridium acetobutylicum (ATCC 824).
N C Moroney et al.
Meat science, 92(4), 423-429 (2012-06-08)
A seaweed extract containing laminarin (L) and fucoidan (F) (L/F) was manufactured from brown seaweed (Laminaria digitata) in spray-dried (L/F-SD) and wet (L/F-WS) forms. The effect of supplementation of pig diets with L/F-SD and L/F-WS (L, 500 mg/kg feed; F
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Questions

1–9 of 9 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. ラミナリンはLPSフリーでしょうか？

    1 answer

    1. This product is isolated from the algae Laminaria digitata. LPS (Lipopolypolysaccharide) is a product of bacteria. During processing, the material is not intentionally exposed to bacteria. The expectation is that this item would have a very low LPS content. However, the product is not tested for the presence of LPS and is not guaranteed to be LPS-free.

      Helpful?

  4. Could you kindly provide the molecular weight of L9634?

    1 answer

    1. The determination of the molecular weight has not been conducted. However, based on archived data, the reported molecular weight for one of the lots is 8,600. We recommend validating this data on your end as we have not conducted specific testing for it.

      Helpful?

  5. Laminarin is considered a neutral polysaccharide. However, at interaction studies with a quartz crystal microbalance and the bound to particles it omitted a negative charge. Is it possible that Laminarin contains negativley charged groups?

    1 answer

    1. The charge state of this product has not been investigated. There are publications available which claim that it is neutral, however the link below is reporting laminarin as negatively charged. Unfortunately, no further information is available.
      https://www.sciencedirect.com/science/article/abs/pii/S0013935123007016

      Helpful?

  6. Pourriez-vous m'indiquer le degré de pureté du produit. Je ne l'ai pas trouvé. Merci

    1 answer

    1. Purity is not reported as a specification for this product.

      Helpful?

  7. How does the storage temperature relate to shipping conditions?

    1 answer

    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

      Helpful?

  8. What is the exact molecular weight (MW) of Product L9634, Laminarin?

    1 answer

    1. Product L9634, Laminarin, is a mixture of different carbohydrates of different MW values.  One publication has done a detailed ESI-MS analysis of laminarin from Laminaria digitata.  Read, S.M., et al., Analysis of the structural heterogeneity of laminarin by electrospray-ionisation-mass spectrometry.  Carbohydrate Res., 281(2), 187-201 (1996).

      Helpful?

  9. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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