I6138

Idazoxan hydrochloride

α2-adrenoceptor antagonist

• Synonim(y): (±)-2-[1,4-Benzodioxan-2-yl]-2-imidazoline hydrochloride, RX 781094
• Wzór empiryczny (zapis Hilla): C₁₁H₁₂N₂O₂ · HCl
• Numer CAS: 79944-56-2
• Masa cząsteczkowa: 240.69
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278493
• NACRES: NA.77
• MDL number: MFCD00069293

Właściwości

• Nazwa produktu: Idazoxan hydrochloride,
• Quality Segment: 100
• solubility: H₂O: 50 mg/mL
• SMILES string: Cl.C1CN=C(N1)C2COc3ccccc3O2
• InChI: 1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4,10H,5-7H2,(H,12,13);1H
• InChI key: MYUBYOVCLMEAOH-UHFFFAOYSA-N
• Gene Information: human ... ADRA2A(150), ADRA2B(151), ADRA2C(152)

Opis

Application

Idazoxan hydrochloride has been used to study the efficacy of antidepressant treatments that interact with multiple neurotransmitter systems.

Biochem/physiol Actions

α2-adrenoceptor antagonist; I2 imidazoline receptor agonist; I1 imidazoline receptor antagonist. Idazoxan can antagonize various behaviors generated by ethanol in a preclinical setting. It possesses neuroprotective activity against spinal cord injury, resulted due to experimental autoimmune encephalomyelitis (EAE) in mouse, an animal modal of multiple sclerosis (MS).

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves