I5782

Anti-Interleukin-22 Receptor, C-Terminal antibody produced in rabbit

~0,5 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonim(y): Anti-IL-22R
• UNSPSC Code: 51111800
• MDL number: MFCD04040428
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: 3

Właściwości

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen ~62 kDa
• species reactivity: human
• concentration: ~0,5 mg/mL
• technique(s): western blot: 0.5-1 μg/mL
• UniProt accession no.: Q8N6P7
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... IL22RA1(58985)

Opis

Immunogen

synthetic peptide corresponding to amino acids 560-574 of human IL-22 receptor precursor.

Biochem/physiol Actions

Interleukin-22 (IL-22) belongs to the IL-10 family of T-cell associated cytokines, highly expressed by Th17 cell subset and also by cells of innate immunity system. The cellular effects of IL-22 are mediated by a heterodimeric receptor made up of IL-22 and IL-10Rβ. IL-22 signaling mediates proliferation of epithelial cells during inflammation mainly by the activation of STAT1 and STAT3 signaling.

Features and Benefits

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Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

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