I3275
Interferon-γ from rat
≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Synonim(y):
IFN-γ
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About This Item
Polecane produkty
pochodzenie biologiczne
rat
Poziom jakości
rekombinowane
expressed in E. coli
Próba
≥97% (SDS-PAGE)
Postać
lyophilized powder
masa cząsteczkowa
15.5 kDa
opakowanie
pkg of 0.1 mg
metody
cell culture | mammalian: suitable
zanieczyszczenia
endotoxin, tested
kolor
white
numer dostępu UniProt
temp. przechowywania
−20°C
informacje o genach
rat ... Ifng(25712)
Zastosowanie
Interferon-γ from rat has been used to study the effect of lipoxin A4 and 17(R)-resolvin D1 on lipopolysaccharide and interferon-γ-mediated tumor necrosis factor release in rat astrocyte culture. In rats, it has been used in the treatment of INS-1 cell culture to study the conversion factors which change the frequency of β-cell replication or apoptosis to rates of replication or apoptosis.
Działania biochem./fizjol.
Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. In rats, it is upregulated during ischemic injury in the embolic stroke. In cultured rat intestinal mucosa microvascular endothelial cells, ifng is responsible for inducing expression of interferon-α and interferon-β.
Cechy i korzyści
The biological activity is measured in an anti-viral assay using L-929 cells infected with EMC virus.
Postać fizyczna
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 50 μg of bovine serum albumin per 1 μg of cytokine.
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produkt powiązany
Numer produktu
Opis
Cennik
Kod klasy składowania
13 - Non Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
Certyfikaty analizy (CoA)
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Meager, A. et al.
Lymphokines and Interferons, A Practical Approach, 129-129 (1987)
Sally Abdelmoaty et al.
PloS one, 8(9), e75543-e75543 (2013-10-03)
Lipoxins and resolvins have anti-inflammatory and pro-resolving actions and accumulating evidence indicates that these lipid mediators also attenuate pain-like behavior in a number of experimental models of inflammation and tissue injury-induced pain. The present study was undertaken to assess if
R Dijkema et al.
The EMBO journal, 4(3), 761-767 (1985-03-01)
The chromosomal immune interferon gene of the rat (IFN-gamma) was identified by screening a recombinant rat lambda phage library with a human IFN-gamma cDNA probe. In contrast to the genes of other rat IFNs, this rat IFN-gamma chromosomal gene contains
Zhen-Jie Wang et al.
iScience, 24(11), 103280-103280 (2021-11-13)
Nitric oxide (NO) is an important immune molecule that acts against extracellular and intracellular pathogens in most hosts. However, after the knockout of inducible nitric oxide synthase (iNOS -/-) in Sprague Dawley (SD) rats, these iNOS -/- rats were found
Hamid Reza Jafarinaveh et al.
Iranian journal of allergy, asthma, and immunology, 13(2), 125-130 (2013-12-18)
Increased levels of proinflammatory cytokines have been recorded after the onset of transient or permanent brain ischemia and are usually associated with exacerbation of ischemic injury. Embolic stroke model is more relevant to the pathophysiological situation in such patients, because
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