G1513

Glycerol formal

47-67% 5-hydroxy-1,3-dioxane basis (GC), 33-53% 4-hydroxymethyl-1,3-dioxolane basis (GC)

• Wzór empiryczny (zapis Hilla): C₄H₈O₃
• Numer CAS: 99569-11-6
• Masa cząsteczkowa: 104.10
• UNSPSC Code: 50161901
• NACRES: NA.25
• PubChem Substance ID: 24895065
• MDL number: MFCD10039829
• Beilstein/REAXYS Number: 103206

Właściwości

• contains: ~0.02% 2,6-di-tert-butyl-4-methylphenol as stabilizer
• composition: 5-hydroxy-1,3-dioxane, 47-67% GC , 4-hydroxymethyl-1,3-dioxolane, 33-53% GC
• refractive index: n20/D 1.451 (lit.)
• bp: 192-193 °C (lit.)
• density: 1.203 g/mL at 25 °C (lit.)
• SMILES string: OCC1COCO1.OC2COCOC2
• InChI: 1S/2C4H8O3/c5-4-1-6-3-7-2-4;5-1-4-2-6-3-7-4/h2*4-5H,1-3H2
• InChI key: JIUMSISXCKWZTA-UHFFFAOYSA-N

Opis

General description

Glycerol formal (GlyF) includes isomers, namely, 4-hydroxymethyl-1,3-dioxolane and 5-hydroxy-1,3-dioxane. It is a glycerol synthon with a combination of two 5- and 6-membered ring isomers.

Application

Glycerol formal is used to to solubilize water-insoluble compounds for subsequent aqueous dilution. It has been used as a chemical and dye emulsifier and as a cosolvent for drug delivery

Glycerol formal is used to to solubilize water-insoluble compounds for subsequent aqueous dilution. It has been used as a chemical and dye emulsifier and as a cosolvent for drug delivery. Glycerol formal was used as a vehicle for antibiotic delivery in rats.

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