E1408

14-3-3 Eta histidine-tagged human

recombinant, expressed in E. coli, C-terminal, ≥90% (SDS-PAGE), buffered aqueous glycerol solution

• Synonim(y): 14-3-3η, 14-3-3F, 14-3-3e, MGC93547, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide, YWHAH, Ywha1
• UNSPSC Code: 12352200

Właściwości

• recombinant: expressed in E. coli
• assay: ≥90% (SDS-PAGE)
• form: buffered aqueous glycerol solution
• mol wt: ~30 kDa (14-3-3 proteins)
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... LOC646954(646954)

Opis

Biochem/physiol Actions

14-3-3 proteins are involved in a multitude of biological processes and play a regulatory role in processes such as apoptotic cell death, mitogenic signal transduction, and cell cycle control.[1][2] 14-3-3η binds various proteins such as the MTLX-2 transcription factor as well as the DNA binding domain of Miz1 transcription factor.[3] 14-3-3η also binds the glucocorticoid receptor, functioning as a positive regulator in the glucocorticoid signaling pathway.[4][5] 14-3-3η is expressed and regulated in nerve cells.

Physical form

Supplied as a 0.2 μm filtered solution in 50 mM Tris-HCl, pH 7.6, 1 mM EDTA, 1 mM DTT, and 20% glycerol (w/v).

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable