C8221

Caffeic acid phenethyl ester

≥97% (HPLC), powder

• Synonim(y): CAPE
• Wzór empiryczny (zapis Hilla): C₁₇H₁₆O₄
• Numer CAS: 104594-70-9
• Masa cząsteczkowa: 284.31
• Numer MDL: MFCD00866470
• Kod UNSPSC: 12352108
• Identyfikator substancji w PubChem: 24278341
• NACRES: NA.77

Właściwości

• pochodzenie biologiczne: synthetic
• Próba: ≥97% (HPLC)
• Formularz: powder
• warunki przechowywania: protect from light
• kolor: off-white
• rozpuszczalność: ethyl acetate: 50 mg/mL; DMSO: soluble; ethanol: soluble
• temp. przechowywania: −20°C
• ciąg SMILES: Oc1ccc(\C=C\C(=O)OCCc2ccccc2)cc1O
• InChI: 1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+
• Klucz InChI: SWUARLUWKZWEBQ-VQHVLOKHSA-N
• informacje o genach: human ... NFKB2(4791)

Opis

Zastosowanie

Caffeic acid phenethyl ester (CAPE) has been used to determine the effect of CAPE in hyperthyroidism,[1] as a component of culture media to measure the cytotoxicity of breast cancer cell line MDA-MB-231,[2] to study its effects on amiodarone-induced pulmonary fibrosis in rats.[3]

Działania biochem./fizjol.

CAPE exhibits several properties such as anticarcinogenic, immunomodulatory activities, antioxidant, antiviral, anti-inflammatory, hypoglycaemic effect, cardioprotective and inhibits gastric secretion.[1] It also has an inhibitory effect on fibroblasts growth factor type 2 (FGF-2), a tumor growth factor in breast cancer.[2]

Caffeic acid phenethyl ester is a specific inhibitor of the nuclear transcription factor NF-κB.

Cechy i korzyści

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: dust mask type N95 (US), Eyeshields, Gloves