C3412

Cyproterone acetate

≥98%

• Synonim(y): 6-Chloro-1β,2β-dihydro-17-hydroxy-3′H-cyclopropa(1,2)-pregna-1,4,6-triene-3,20-dione acetate
• Wzór empiryczny (zapis Hilla): C₂₄H₂₉ClO₄
• Numer CAS: 427-51-0
• Masa cząsteczkowa: 416.94
• NACRES: NA.77
• PubChem Substance ID: 24278309
• UNSPSC Code: 41116107
• EC Number: 207-048-3
• MDL number: MFCD00864671
• Assay: ≥98%
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98%
• form: powder
• storage temp.: 2-8°C
• SMILES string: [H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])C=C(Cl)C4=CC(=O)[C@@H]5C[C@@H]5[C@]34C
• InChI: 1S/C24H29ClO4/c1-12(26)24(29-13(2)27)8-6-16-14-10-20(25)19-11-21(28)15-9-18(15)23(19,4)17(14)5-7-22(16,24)3/h10-11,14-18H,5-9H2,1-4H3/t14-,15+,16-,17-,18-,22-,23-,24-/m0/s1
• InChI key: UWFYSQMTEOIJJG-FDTZYFLXSA-N
• Gene Information: human ... AR(367), NR3C1(2908), PGR(5241) ; mouse ... Nr3c1(14815) ; rat ... Ar(24208)

Opis

Application

Cyproterone acetate has been used to study its effects on insulin-like growth factor I secretion.

Biochem/physiol Actions

Cyproterone acetate is a synthetic steroid and an androgen antagonist. It is a potent inhibitor of leukocyte migration through endothethial cell monolayers. Cyproterone acetate acts as a liver tumor promoter in experimental animal model.[1] Liver tumor promotion appears to be female gender-specific, as formation of an active metabolite that forms DNA adducts.[2]

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Informacja o środkach bezpieczeństwa

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H312 + H332,H351
• pcodes: P202 - P261 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 2
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges