C3025

(±)-Chlorpheniramine maleate salt

≥99% (perchloric acid titration)

• Wzór empiryczny (zapis Hilla): C₁₆H₁₉ClN₂ · C₄H₄O₄
• Numer CAS: 113-92-8
• Masa cząsteczkowa: 390.86
• NACRES: NA.77
• PubChem Substance ID: 24277767
• UNSPSC Code: 12352116
• EC Number: 204-037-5
• MDL number: MFCD00069225
• Assay: ≥99% (perchloric acid titration)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥99% (perchloric acid titration)
• form: powder
• mp: 130-135 °C (lit.)
• originator: Bayer
• SMILES string: CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.O=C(/C=C\C(O)=O)O
• InChI: 1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI key: DBAKFASWICGISY-BTJKTKAUSA-N
• Gene Information: human ... HRH1(3269)

Opis

General description

Chlorpheniramine maleate (CPM)/(3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine is an alkylamine antihistamine.

Application

(±)-Chlorpheniramine maleate salt has been used:

• as H1 receptor antagonist to determine the receptor function
• to block the effect of compound 48/80 on plasma IGF-I
• as a standard for fast sensing and determination by sequential injector coupled with potentiometer

Biochem/physiol Actions

H₁ Histamine receptor antagonist.

Chlorpheniramine maleate (CPM) can prevent rhinitis and urticaria. It is used to cure several allergic conditions. This antihistamine is used in small-animal veterinary practices.

Features and Benefits

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges