C1860

Anti-Clathrin Heavy Chain antibody, Mouse monoclonal

clone TD.1, purified from hybridoma cell culture

• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD00162235
• Conjugate: unconjugated
• Clone: TD.1, monoclonal
• Application: ARR, ICC, IP, WB
• Citations: 10

Właściwości

• biological source: mouse
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: TD.1, monoclonal
• form: buffered aqueous solution
• mol wt: antigen 180-192 kDa
• species reactivity: rat, human, bovine, mouse
• concentration: ~2 mg/mL
• technique(s): immunocytochemistry: suitable, immunoprecipitation (IP): suitable, microarray: suitable, western blot: 2-4 μg/mL using whole extract of cultured rat adrenal pheochromocytoma PC-12 cells.
• isotype: IgG1
• UniProt accession no.: Q00610
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CLTC(1213) ; mouse ... Cltc(67300) ; rat ... Cltc(54241)

Opis

General description

Clathrin, a three legged structure refer as triskelion is the main component of polygonal network and forms the coat of coated vesicles and coated pits. Clathrin-coated vesicles accounts for receptor mediated endocytosis at the plasma membrane and also play a crucial role in hormone secretion and mechanism of action. Monoclonal Anti-Clathrin Heavy Chain antibody can be used to study the mechanism of clathrin mediated membrane trafficking during hormonal stimulation and protein phosphorylation. Mouse monoclonal anti-clathrin heavy chain antibodies are react specifically with clathrin heavy chain CHC17 but do not cross react with muscle isoform CHC22.

Immunogen

globular N-terminal domain of bovine clathrin heavy chain.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Monoclonal Anti-Clathrin Heavy Chain antibody can be used in immunoblotting. It can also be used in western blotting to characterize clathrin heavy chain levels

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Klasa składowania: 12 - Non Combustible Liquids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable