B9688

Pizotifen

≥98% (HPLC)

• Synonim(y): Pizotifen, Pizotyline; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine
• Wzór empiryczny (zapis Hilla): C₁₉H₂₁NS
• Numer CAS: 15574-96-6
• Masa cząsteczkowa: 295.44
• NACRES: NA.77
• PubChem Substance ID: 329773323
• UNSPSC Code: 12352200
• EC Number: 239-632-9
• MDL number: MFCD00864192
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• assay: ≥98% (HPLC)
• form: powder
• solubility: DMSO: ≥8 mg/mL
• originator: Novartis
• storage temp.: room temp
• SMILES string: CN1CCC(\CC1)=C2\c3ccccc3CCc4sccc24
• InChI: 1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
• InChI key: FIADGNVRKBPQEU-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

Pizotifen is a Serotonin antagonist used for prophylaxis of migraine

Pizotifen is a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity. It is used for the prevention of vascular headache including migraine and cluster headache.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable