B6936

3-Benzidino-6-(4-chlorophenyl)pyridazine

≥98% (HPLC), solid

• Synonim(y): BCP
• Wzór empiryczny (zapis Hilla): C₂₂H₁₇N₄Cl
• Numer CAS: 901773-91-9
• Masa cząsteczkowa: 372.85
• NACRES: NA.77
• PubChem Substance ID: 329773289
• UNSPSC Code: 12352202
• MDL number: MFCD11046030
• Assay: ≥98% (HPLC)
• Form: solid

Właściwości

• assay: ≥98% (HPLC)
• form: solid
• color: light yellow
• solubility: DMSO: >14 mg/mL
• storage temp.: 2-8°C
• SMILES string: Nc1ccc(cc1)-c2ccc(Nc3ccc(nn3)-c4ccc(Cl)cc4)cc2
• InChI: 1S/C22H17ClN4/c23-18-7-1-17(2-8-18)21-13-14-22(27-26-21)25-20-11-5-16(6-12-20)15-3-9-19(24)10-4-15/h1-14H,24H2,(H,25,27)
• InChI key: ABGCSSPCKSVMHI-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents.

3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents. The IC50 values for the blocking action of BCP on IKDR and IKA was calculated as 7.13 μM and 0.55 μM, respectively in acutely isolated rat hippocampal pyramidal neurons by using whole-cell patch-clamp technique. The parent compound, minaprine (Cat. No. M3157), has selective affinity for M1 muscarinic receptors and possesses memory-enhancing properties and also acts as an antidepressant.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves