B5438

Balsalazide disodium salt hydrate

• Synonim(y): 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt hydrate
• Wzór empiryczny (zapis Hilla): C₁₇H₁₃N₃Na₂O₆ · xH₂O
• Numer CAS: 213594-60-6
• Masa cząsteczkowa: 401.28 (anhydrous basis)
• NACRES: NA.25
• PubChem Substance ID: 329773261
• UNSPSC Code: 12352100
• MDL number: MFCD18632541

Właściwości

• assay: ≥99% (HPLC)
• form: powder
• storage temp.: 2-8°C
• SMILES string: O.[Na+].[Na+].Oc1ccc(cc1C([O-])=O)\N=N\c2ccc(cc2)C(=O)NCCC([O-])=O
• InChI: 1S/C17H15N3O6.2Na.H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;1H2/q;2*+1;/p-2/b20-19+;;;
• InChI key: ZZZXQZHSFPVNCR-HVARVCSCSA-L

Opis

Biochem/physiol Actions

Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals. Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa. It was also shown to inhibit azoxymethane-induced colon carcinogenesis. In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable