95200

Vitamin B_12a hydrochloride

≥96% (UV), ≥96% (HPLC)

• Synonim(y): Hydroxocobalamin hydrochloride
• Wzór empiryczny (zapis Hilla): C₆₂H₈₉CoN₁₃O₁₅P · HCl
• Numer CAS: 59461-30-2
• Masa cząsteczkowa: 1382.82
• Numer WE: 261-772-4
• Numer MDL: MFCD00167463
• Kod UNSPSC: 12352205
• Identyfikator substancji w PubChem: 57653658
• NACRES: NA.79

Właściwości

• pochodzenie biologiczne: fermentation/recombinant
• Poziom jakości: 100
• Próba: ≥96% (HPLC); ≥96% (UV)
• Postać: powder or crystals
• strata: ≤12% loss on drying, 20 °C (HV)
• kolor: red to dark red
• rozpuszczalność: methanol: 10 mg/mL at 20 °C, clear, dark red
• temp. przechowywania: 2-8°C
• ciąg SMILES: Cl.C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)[C@H]2N([Co+]O)C1=C(C)C3=NC(=CC4=NC(=C(C)C5=N[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]5CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78
• InChI: 1S/C62H90N13O14P.ClH.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H;;1H2/q;;+3;/p-3/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;;/m1.../s1
• Klucz InChI: KEHNCSYXYMMUCO-BXSGNKEGSA-K

Opis

Zastosowanie

Vitamin B12a hydrochloride has been used as an antidote for cyanide poisoning.

Działania biochem./fizjol.

Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms. Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine.

Inne uwagi

Review

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)