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For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
81709
L-Proline
≥99.5% (NT), suitable for cell culture, BioUltra
Synonim(y):
(S)-Pyrrolidine-2-carboxylic acid
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Nazwa produktu
L-Proline, BioUltra, ≥99.5% (NT)
product line
BioUltra
Quality Level
assay
≥99.5% (NT)
form
powder or crystals
optical activity
[α]20/D −85.0±1.0°, c = 5% in H2O
technique(s)
cell culture | mammalian: suitable
impurities
insoluble matter, passes filter test, ≤0.3% foreign amino acids
ign. residue
≤0.1%
loss
≤0.1% loss on drying, 20 °C (HV)
color
colorless to white
pH
6.0-7.0 (25 °C, 1 M in H2O)
mp
228 °C (dec.) (lit.)
solubility
H2O: 1 M at 20 °C, clear, colorless
anion traces
chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤100 mg/kg
cation traces
Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, NH4+: ≤20 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg
λ
1 M in H2O
UV absorption
λ: 260 nm Amax: 0.05, λ: 280 nm Amax: 0.05
SMILES string
OC(=O)[C@@H]1CCCN1
InChI
1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
InChI key
ONIBWKKTOPOVIA-BYPYZUCNSA-N
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Ta pozycja | |||
|---|---|---|---|
| form powder or crystals | form powder | form - | form - |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) - |
| assay ≥99.5% (NT) | assay 98.5-101.0% dry basis | assay - | assay 99% |
| product line BioUltra | product line - | product line TraceCERT® | product line - |
| optical activity [α]20/D −85.0±1.0°, c = 5% in H2O | optical activity [α]20/D -86.0 to -84.0 °, c = 4 in water, [α]25/D -86.3 to -84.3°, c = 4 in water | optical activity - | optical activity [α]20/D −84°, c = 4 in H2O |
| solubility H2O: 1 M at 20 °C, clear, colorless | solubility H2O: 50 mg/mL | solubility - | solubility - |
Application
- Synthesis and in silico inhibitory action studies of azo-anchored imidazo[4,5-b]indole scaffolds against the COVID-19 main protease (M(pro)).: This publication discusses the synthesis of novel compounds using L-Proline and their potential as inhibitors against COVID-19, contributing to the ongoing search for effective treatments (Geedkar et al., 2024).
Other Notes
Klasa składowania
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Produkty
Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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