61962

Betaine

BioUltra, ≥99.0% (NT)

• Synonim(y): (Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine
• Wzór liniowy: (CH₃)₃N⁺CH₂COO^-
• Numer CAS: 107-43-7
• Masa cząsteczkowa: 117.15
• UNSPSC Code: 41116107
• NACRES: NA.25
• PubChem Substance ID: 57651874
• EC Number: 203-490-6
• Beilstein/REAXYS Number: 3537113
• MDL number: MFCD00012123

Właściwości

• product line: BioUltra
• Quality Segment: 200
• assay: ≥99.0% (NT)
• impurities: insoluble matters, passes filter test
• solubility: methanol: 1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤200 mg/kg, sulfate (SO₄^2-): ≤200 mg/kg
• cation traces: Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤100 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg, Ca: ≤20 mg/kg
• absorption: ≤0.05 at 280 nm in methanol at 1 M, ≤0.09 at 260 nm in methanol at 1 M
• SMILES string: C[N+](C)(C)CC([O-])=O
• InChI: 1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
• InChI key: KWIUHFFTVRNATP-UHFFFAOYSA-N

Opis

General description

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Application

Betaine has been used in reverse transcription to increase the thermal stability of proteins and to destabilize the DNA helix.

Biochem/physiol Actions

Betaine has been shown to increase S-adenosylmethionine (SAM) levels and hence, may have a role in diminishing hepatic steatosis. It is an osmolyte which protects cells against environmental stress.[1][2]

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)