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22049

Sigma-Aldrich

λ-Carrageenan

plant mucopolysaccharide

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About This Item

Numer CAS:
9064-57-7
Numer WE:
232-953-5
Numer MDL:
MFCD00151513
Kod UNSPSC:
12352201
NACRES:
NA.25

pochodzenie biologiczne

plant

Formularz

solid

kolor

light yellow

temp. przechowywania

room temp

InChI

1S/C24H42O39S6/c25-1-5-9(27)11(29)18(61-67(42,43)44)22(54-5)57-15-8(4-52-65(36,37)38)56-23(19(13(15)31)62-68(45,46)47)59-16-10(28)6(2-26)55-24(20(16)63-69(48,49)50)58-14-7(3-51-64(33,34)35)53-21(32)17(12(14)30)60-66(39,40)41/h5-32H,1-4H2,(H,33,34,35)(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)/p-6/t5-,6-,7-,8-,9+,10+,11+,12+,13+,14+,15+,16+,17-,18-,19-,20-,21+,22+,23-,24+/m1/s1

Klucz InChI

CFLYIPGVTFOQCI-SQESNNFJSA-H

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Opis ogólny

Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents.
non-gelling at 1% in 0.2 M KCl-solution

Zastosowanie

Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. Non-gelling λ-carrageenan is used to induce inflammation and inflammatory pain in the rodent hindpaw or air pouch models. More recently carrageenan has been injected directly into the joints of rodents to model arthritic pain and inflammation.

Komentarz do analizy

solubility:
10 mg/mL in H2O : clear to very hazy, colorless to faint yellow

Inne uwagi

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number
BCBP8978V
BCBP7001V
BCBP3274V
BCBP3273V
BCBN6085V

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Jeśli potrzebujesz konkretnej wersji, możesz wyszukać konkretny certyfikat według numeru partii lub serii.

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Influence of dicephalic ionic surfactant interactions with oppositely charged polyelectrolyte upon the In vitrodye release from oil core nanocapsules.
Bazylinska U, Skrzela R, et al.
Bioelectrochemistry, doi: 10-doi: 10 (2011)
Refat M Hassan et al.
Carbohydrate research, 346(14), 2260-2267 (2011-08-30)
The kinetics of oxidation of iota- and lambda-carrageenan as sulfated carbohydrates by permanganate ion in aqueous perchlorate solutions at a constant ionic strength of 2.0 mol dm(-3) have been investigated spectrophotometrically. The pseudo-first-order plots were found to be of inverted
Vanessa Pirrone et al.
Virology journal, 9, 33-33 (2012-01-28)
Continued efforts are being directed toward the development of microbicides that will be used to reduce or eliminate the risk of HIV-1 sexual transmission. Unfortunately, clinical trials involving polyanion-containing microbicide formulations, including Carraguard (λ-carrageenan [LC]) and Ushercell (cellulose sulfate [CS])
Tetsuro Nikai et al.
Pain, 139(3), 533-540 (2008-08-30)
Sumatriptan and the other triptan drugs target the serotonin receptor subtypes1B, 1D, and 1F (5-HT(1B/D/F)), and are prescribed widely in the treatment of migraine. An anti-migraine action of triptans has been postulated at multiple targets, within the brain and at
K Mitchell et al.
Neuroscience, 158(2), 885-895 (2008-11-27)
During peripheral tissue inflammation, inflammatory processes in the CNS can be initiated by blood-borne pro-inflammatory mediators. The choroid plexus, the site of cerebrospinal fluid (CSF) production, is a highly specialized interface between the vascular system and CNS, and thus, this
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Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Can you give me information about the molecular weight of lambda carrageenan?

    1 answer

    1. The molecular weight is not determined for this product. However, the literature states that the molecular weight for lambda Carrageenan is 446 kDa (number average) and 990 kDa (weight average) by ICP-AES (inductively coupled plasma-atomic emission spectrometry.

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