06892

(+)-Lariciresinol

≥95.0% (HPLC)

• Synonim(y): (2S,3R,4R)-Tetrahydro-2-(4-hydroxy-3-methoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-furanmethanol, 4-[(2S,3R,4R)-4-[(4-Hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)oxolan-2-yl]-2-methoxyphenol, NSC 329247
• Wzór empiryczny (zapis Hilla): C₂₀H₂₄O₆
• Numer CAS: 27003-73-2
• Masa cząsteczkowa: 360.40
• Beilstein: 4560057
• Numer MDL: MFCD07784476
• Kod UNSPSC: 12352005
• Identyfikator substancji w PubChem: 329748296
• NACRES: NA.25

Właściwości

• Próba: ≥95.0% (HPLC)
• Postać: powder
• Zastosowanie: metabolomics; vitamins, nutraceuticals, and natural products
• ciąg SMILES: COc1cc(C[C@H]2CO[C@@H]([C@H]2CO)c3ccc(O)c(OC)c3)ccc1O
• InChI: 1S/C20H24O6/c1-24-18-8-12(3-5-16(18)22)7-14-11-26-20(15(14)10-21)13-4-6-17(23)19(9-13)25-2/h3-6,8-9,14-15,20-23H,7,10-11H2,1-2H3/t14-,15-,20+/m0/s1
• Klucz InChI: MHXCIKYXNYCMHY-AUSJPIAWSA-N

Opis

Opis ogólny

Lariciresinol(LA) is a dietary phytoestrogen plant lignan. It is one of the main active phytochemicals in many traditional medicinal plants and cereals.

Zastosowanie

Lariciresinol has been used as a reference standard:

• in the purification, identification, and analysis of lignan phytoestrogens and lignan glycosides
• for the determination of the enantiomeric composition of lariciresinol from the pinoresinol to lariciresinol reduction reaction using high-performance liquid chromatography (HPLC)
• forqualitative and quantitative analysis of lignans in seven types of triticalegrain using ultra-performance liquid chromatography (UPLC)

Działania biochem./fizjol.

Lariciresinol is a potent dietary antioxidant and a radical scavenger by potentially chelating catalytic Fe²⁺ ions. It exerts antimicrobial effects against foodborne pathogens S. aureus and E. coli O157:H7. Lariciresinol is an effective anticancer agent that inhibits cell proliferation and induces apoptosis in human HepG2 cells in vitro. It also displays anti-inflammatory and anti-diabetic effects in vitro and in vivo studies respectively.

Opakowanie

Bottomless glass bottle. Contents are inside inserted fused cone.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS09
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H400
• Zwroty wskazujące środki ostrożności: P273 - P391 - P501
• Klasyfikacja zagrożeń: Aquatic Acute 1
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable