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Merck

M0200000

Mannitol

European Pharmacopoeia (EP) Reference Standard

Synonim(y):

D-Mannitol, Mannite

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About This Item

Wzór empiryczny (zapis Hilla):
C6H14O6
Numer CAS:
Masa cząsteczkowa:
182.17
Beilstein:
1721898
Numer MDL:
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
NACRES:
NA.24

klasa czystości

pharmaceutical primary standard

rodzina API

mannitol

producent / nazwa handlowa

EDQM

mp

167-170 °C (lit.)

Zastosowanie

pharmaceutical (small molecule)

format

neat

ciąg SMILES

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

Klucz InChI

FBPFZTCFMRRESA-KVTDHHQDSA-N

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Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the Issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for the preparation of the below-given solutions as per European Pharmacopoeia:

  • Reference solution (b) in the testing of related substances using liquid chromatography (General text 2.2.29) in isomalt, according to the monograph 1531
  • Reference solutions (a) in the identification of mannitol using thin-layer chromatography (General text 2.2.27) and infra-red spectroscopy and testing of related substances and assay using liquid chromatography (General text 2.2.29), according to the monograph 0559
  • Reference solution (b) in the identification of sorbitol using thin-layer chromatography (General text 2.2.27), according to the monograph 0435
  • Reference solution (b) in the testing of related substances using gas chromatography (General text 2.2.28), according to the monograph 1381

Działania biochem./fizjol.

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Opakowanie

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Inne uwagi

Sales restrictions may apply.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1


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Certyfikaty analizy (CoA)

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Bronchiectasis is characterised by excessive production of mucus and pulmonary exacerbations. Inhaled osmotic agents may enhance mucociliary clearance, but few long-term clinical trials have been conducted. To determine the impact of inhaled mannitol on exacerbation rates in patients with non-cystic

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