I0060000

Ifosfamide

European Pharmacopoeia (EP) Reference Standard

• Synonim(y): Ifex, N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide
• Wzór empiryczny (zapis Hilla): C₇H₁₅Cl₂N₂O₂P
• Numer CAS: 3778-73-2
• Masa cząsteczkowa: 261.09
• NACRES: NA.24
• PubChem Substance ID: 329815295
• UNSPSC Code: 41116107
• MDL number: MFCD00057374

Właściwości

• grade: pharmaceutical primary standard
• API family: ifosfamide
• manufacturer/tradename: EDQM
• technique(s): HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: ClCCNP1(=O)OCCCN1CCCl
• InChI: 1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)
• InChI key: HOMGKSMUEGBAAB-UHFFFAOYSA-N

Opis

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ifosfamide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Ifosfamide is a nitrogen mustard compound that is a structural isomer of cyclophosphamide. Ifosfamide is a prodrug that must be transformed by cytochrome P450 to the biologically active component. It is used as an antineoplastic agent in cancer chemotherapy, but ifosfamide is more likely to cause renal toxicity than cyclophosphamide.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06,GHS08
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H301,H319,H340,H350,H360FD
• Ostrzeżenia: P202 - P264 - P280 - P301 + P310 + P330 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 1B
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable