This item is a product of the European Pharmacopoeia, intended for use as an analytical standard. The product has not been tested for suitability of cell culture. The research grade product F6127 is tested for solubility at 50 mg/mL in ethanol. Similar rates would be expected for this item. Stock solutions may be filter sterilized. The solution stability is not determined. However, various sources state that stock solutions Fludrocortisone acetate , when stored at -80°C, are stable for at least 2 years. At -20°C, stability is typically around 1 year. For short-term storage (days to weeks), storage at 0-4°C is recommended.
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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C23H31FO6
Numer CAS:
Masa cząsteczkowa:
422.49
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
pharmaceutical primary standard
API family
fludrocortisone
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
pharmaceutical
format
neat
storage temp.
2-8°C
SMILES string
CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C
InChI
1S/C23H31FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h10,16-18,27,29H,4-9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1
InChI key
SYWHXTATXSMDSB-GSLJADNHSA-N
Gene Information
human ... NR3C2(4306)
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Fludrocortisone acetate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions
Fludrocortisone acetate is a synthetic corticosteroid with more mineralocorticoid than glucocorticoid activity.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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Słowo ostrzegawcze
Warning
Kody zagrożeń
Ostrzeżenia
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
Klasa składowania
11 - Combustible Solids
Co się dzieje?
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
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How to reconstitute Fludrocortisone acetate for cell culture usage? Can the reconstituted solution be filtered with 0.22um? Re the reconstituted solution: what is the storage temp and for how long? how long it's stable in culture medium at 37c?
1 answer-
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