A0225000

Acitretin

European Pharmacopoeia (EP) Reference Standard

• Synonim(y): 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
• Wzór empiryczny (zapis Hilla): C₂₁H₂₆O₃
• Numer CAS: 55079-83-9
• Masa cząsteczkowa: 326.43
• NACRES: NA.24
• PubChem Substance ID: 329770586
• UNSPSC Code: 41116107
• MDL number: MFCD00866632
• eCl@ss: 25140904

Właściwości

• grade: pharmaceutical primary standard
• API family: acitretin
• manufacturer/tradename: EDQM
• application(s): pharmaceutical (small molecule); pharmaceutical
• format: neat
• storage temp.: 2-8°C
• SMILES string: COc1cc(C)c(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)c(C)c1C
• InChI: 1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+
• InChI key: IHUNBGSDBOWDMA-AQFIFDHZSA-N
• Gene Information: human ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258)

Opis

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Acitretin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Synthetic retinoid that is a metabolite of etretinate. Preferentially binds to cellular retinoic acid binding proteins (CRABPs).

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08,GHS07,GHS09
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H315,H319,H360,H410
• Ostrzeżenia: P201 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Co się dzieje?: WGK 3