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SCT065

Green-AlDeSense ALDH1A1 Live Cell Dye

Name: Green-AlDeSense ALDH1A1 Live Cell Dye
Brand: MM
Price: 2660 PLN
Availability: InStock

ALDH1A1 isoform specific live cell dye which labels cancer stem cells for fluorescent microscopy, flow cytometry and in vivo applications.

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Do Państwa/SKU	Dostępność	Cena netto
1 kit	Przewidywany termin wysyłki25 sierpnia 2026zKuehne + Nagel Sp. z o.o.	2660,00 zł

Informacje o tej pozycji

NACRES:

NA.47

UNSPSC Code:

12352207

2660,00 zł

Przewidywany termin wysyłki25 sierpnia 2026Szczegóły

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Właściwości

detection method

fluorometric

Opis

General description

Cancer stem cells (CSCs) have an increased capacity to activate antiapoptotic/prosurvival pathways as well as overexpressing ATP-binding cassette transporters which act as potent efflux pumps for potential chemotherapeutics. Aldehyde dehydrogenases (ALDH), in particular the ALDH1A1 isoform, is believed to be a reliable marker of CSCs across many cancer types, including prostate, lung, breast, esophageal, and ovarian cancers. ALDH1A1 is associated with increased chemotherapy resistance and poor clinical outcome and is an established stem cell marker.

Current methods to identify ALDH in living cells are limited by cross-reactivity with several ALDH isoforms producing difficulties in data analysis and prognosis. Chan, et al. have created a ALDH1A1 isoform specific live cell dye termed Green-AlDeSense which labels cancer stem cells and exhibits a 20-fold fluorescent enhancement when bound to ALDH1A1. The dye identifies ALDH1A1 positive CSCs using live cell imaging, flow cytometry and in vivo studies.

Spectral Properties: absmax: 496 nm, emmax: 516 nm.

Preparation Note

Store at -20C. Protect from light.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Ta pozycja	SCT211	SCT041	SCT069
Sigma-Aldrich SCT065 Green-AlDeSense ALDH1A1 Live Cell Dye	Sigma-Aldrich SCT211 BioTracker Green Sulfane Sulfur live cell dye	Sigma-Aldrich SCT041 BioTracker Green Copper Live Cell Dye	Sigma-Aldrich SCT069 Barwnik do żywych komórek BioTracker ATP-LW
description ALDH1A1 isoform specific live cell dye which labels cancer stem cells for fluorescent microscopy, flow cytometry and in vivo applications.	description Live Cell imaging probe for sulfane sulfur species including persulfide (R-S-SH), polysulfide (R-S-S<sub>n</sub>-S-R) and ploysulfide (H<sub>2</sub>S<sub>n</sub>).	description Live Cell imaging probe for detection of Copper (Cu+) ion in live cells.	description Live cell imaging dye for simultaneous visualization of cellular Adenosine-5′-Triphosphate (ATP) and peroxynitrite (ONOO-).
detection method fluorometric	detection method fluorometric	detection method fluorometric	detection method fluorometric

Klasa składowania

11 - Combustible Solids

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