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Merck

MAB8701

Anti-Dengue Virus Type I Antibody, clone 15F3-1

clone 15F3-1, Chemicon®, from mouse

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Informacje o tej pozycji

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
15F3-1, monoclonal
Species reactivity:
human
Application:
IF
Citations:
1
Pomoc techniczna
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Pozwól nam pomóc

biological source

mouse

Quality Level

antibody form

purified antibody

clone

15F3-1, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable

isotype

IgG1

shipped in

wet ice

General description

Dengue fever is an acute, mosquito-transmitted viral disease characterized by fever, headache, arthralgia (severe retro-orbital pain), myalgia, rash, nausea, and vomiting. Infections are caused by any of the four closely related, but antigenically distinct virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). Infection with one of these serotypes does not provide cross-protective immunity, so persons living in a dengue-endemic area can have four dengue infections during their lifetimes. Dengue is primarily an urban disease of the tropics, and the viruses that cause it are maintained in a cycle that involves humans and Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans. Although most dengue infections result in relatively mild illness, some can produce Dengue Hemorrhagic Fever (DHF) or dengue shock syndrome, with children being particularly at risk. Although epidemic outbreaks have been reported since 1779, the incidence has been increasing, with global, multiple serotype pandemics intensifying within the last 15 years. There is no specific antiviral therapy for dengue, but for both classical dengue and dengue hemorrhagic fever, symptomatic and supportive measures are effective. Important risk factors for DHF include the strain and serotype of the virus involved, as well as the age, immune status, and genetic predisposition of the patient.

Immunogen

Dengue type 1 (Hawaiian) virus antigen.

Application

Anti-Dengue Virus Type I Antibody, clone 15F3-1 detects level of Dengue Virus Type I & has been published & validated for use in IF.
Immunofluorescent assay. Final working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts with the Dengue type 1 virus. May show reactivity with Dengue type 2 virus.

Physical form

0.02M Phosphate Buffer, pH 7.6, 0.25M NaCl and 0.1% sodium azide.
Format: Purified

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Klasa składowania

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Sambashiva Banala et al.
ACS chemical biology, 8(10), 2127-2132 (2013-08-15)
Detection of antibodies is essential for the diagnosis of many diseases including infections, allergies, and autoimmune diseases. Current heterogeneous immunoassays require multiple time-consuming binding and washing steps, which limits their application in point-of-care diagnostics and high-throughput screening. Here, we report

Numer pozycji handlu globalnego

SKUNUMER GTIN
MAB870104053252661792

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