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582243

Tetanus Toxin

Name: Tetanus Toxin
Brand: MM
Price: 1160 PLN
Availability: InStock

from Clostridium tetanim, toxin, lyophilized

Synonim(y):

Tetanus Toxin, Clostridium tetani

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Rozmiar/SKU	Dostępność	Cena netto
25 μg	Dostępne do wysyłki DZISIAJzKuehne + Nagel Sp. z o.o.	1160,00 zł

Informacje o tej pozycji

Numer CAS:

676570-37-9

UNSPSC Code:

12352200

NACRES:

NA.77

Form:

lyophilized

Storage condition:

OK to freeze

1160,00 zł

Dostępne do wysyłki DZISIAJSzczegóły

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Właściwości

Nazwa produktu

Tetanus Toxin, Clostridium tetani, Tetanus toxin is produced by Clostridium tetani. Composed of a 100 kDa heavy and a 50 kDa light chain joined by a single interchain disulfide bond.

description

RTECS - XW5807000

Quality Segment

100

form

lyophilized

manufacturer/tradename

Calbiochem^®

availability

not available in Canada,

storage condition

OK to freeze

solubility

soluble (Please refer to the vial label for lot-specific reconstitution volume.)

storage temp.

2-8°C

Opis

General description

Produced by the anaerobic bacillus Clostridium tetani. Tetanus toxin is one of the deadliest toxins known. Composed of two polypeptide chains joined by a single interchain disulfide bond. The heavy chain (100 kDa) participates in binding to the nerve terminals, internalization, retrograde axonal transport, and membrane translocation of the light chain (50 kDa) into the neuronal cytosol. The light chain inhibits neurotransmitter release after reduction of the disulfide bridge.

Tetanus toxin is produced by Clostridium tetani. Composed of a 100 kDa heavy and a 50 kDa light chain joined by a single interchain disulfide bond.

Biochem/physiol Actions

Binds G_T1b ganglioside in a hemagglutination assay

Primary Target
Tetanus toxin is one of the deadliest toxins known

Product does not compete with ATP.

Preparation Note

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.

Please refer to the vial label for lot-specific reconstitution volume.

Analysis Note

Single band by SDS-PAGE

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Montecucco, C., et al. 1994. FEBS Lett. 346, 92.
Wellhöner, H.H., et al. 1987. J. Biol. Chem. 262, 17374.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Highly Toxic (H)

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Ta pozycja	582235	322326	516560
Sigma-Aldrich 582243 Tetanus Toxin, Clostridium tetani	Sigma-Aldrich 582235 Tetanus Toxin, C-Fragment, Clostridium tetani	Sigma-Aldrich 322326 Diphtheria Toxin, Unnicked, Corynebacterium diphtheriae	Sigma-Aldrich 516560 Pertussis Toxin, Bordetella pertussis
description Tetanus toxin is produced by Clostridium tetani. Composed of a 100 kDa heavy and a 50 kDa light chain joined by a single interchain disulfide bond.	description The C-terminal binding portion of the heavy chain of tetanus toxin.	description Diphtheria toxin catalyzes ADP-ribosylation of eukaryotic aminoacyltransferase II (EF2) using NAD as substrate. Activation requires nicking with a protease followed by reduction with DTT.	description This Pertussis toxin, CAS 70323-44-3, catalyzes ADP-ribosylation of guanine nucleotide-binding regulatory proteins Gi, Go, and Gt.
form lyophilized	form lyophilized	form solid	form lyophilized
manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
storage condition OK to freeze	storage condition OK to freeze	storage condition OK to freeze	storage condition do not freeze
solubility soluble (Please refer to the vial label for lot-specific reconstitution volume.)	solubility sterile distilled water: soluble	solubility soluble (Aqueous buffers or H2O. Please see vial label for lot-specific reconstitution volume.)	solubility soluble (Reconstitute with 500 µl H2O. Obtain a uniform suspension before each use by scraping the walls of the tube and gently pipetting the solution to mix.)