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5120-OP

Guanidine Isothiocyanate

OmniPur® Grade, >=99.0%, Protein denaturant

Synonim(y):

OmniPur® Guanidine Isothiocyanate, GITC, GTC, Guanidine thiocyanate, Guanidinium isothiocyanate, Guanidinium rhodanide, Guanidinium thiocyanate

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Informacje o tej pozycji

Numer CAS:
593-84-0
UNSPSC Code:
12352107
NACRES:
NA.21
MDL number:
MFCD00013027
Pomoc techniczna
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Pozwól nam pomóc

Quality Segment

100

form

crystalline powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

shipped in

ambient

SMILES string

[S-]C#N.[N+H3]C(=N)N

InChI

1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H

InChI key

ZJYYHGLJYGJLLN-UHFFFAOYSA-N

General description

Protein denaturant used to inactivate RNases during isolation of RNA from cell lysates. Molecular biology grade.

Specifications:
A (280 nm, 70%, water): ≤0.8AU
Assay: ≥99.0%
DNase: None detected
Melting point: 118-121°C
Protease: None detected
RNase: None detected
Solubility (70%, water): To pass test





Intended for laboratory and manufacturing use only. Not for drug, food, or household use.

Application


  • Collection and transportation of SARS-CoV-2 and influenza A virus diagnostic samples: Optimizing the usage of guanidine-based chaotropic salts for enhanced biosafety and viral genome preservation: This study emphasizes the critical role of guanidine isothiocyanate in the preservation of viral genomes during the collection and transport of diagnostic samples, thereby enhancing biosafety protocols in molecular biology applications (Komu JG et al., 2024).

  • How to better select SARS-CoV-2 preservation solution of virus nucleic acid testing: Focuses on optimizing viral RNA preservation using solutions containing guanidine isothiocyanate, contributing to more accurate diagnostics in virology (Duan X et al., 2023).

  • Visual Detection of Chicken Adulteration Based on a Lateral Flow Strip-PCR Strategy: Demonstrates the application of guanidine isothiocyanate in developing rapid diagnostic tools for food safety, enhancing the detection of adulterants in chicken products (Xu H et al., 2022).

  • Using discrete event simulation to optimize nucleic acid testing process for coronavirus disease 2019 (COVID-19): Describes how guanidine isothiocyanate enhances the efficiency of COVID-19 testing processes, aiding in faster diagnosis and better pandemic management (Guan W et al., 2022).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany
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pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C

supp_hazards

EUH032

Klasa składowania

8B - Non-combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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