164610

Octan p-aminofenylomocznika

≥90% (HPLC), MMP activator, solid

• Synonim(y): APMA
• Wzór empiryczny (zapis Hilla): C₈H₉HgNO₂
• Numer CAS: 6283-24-5
• Masa cząsteczkowa: 351.75
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00007820
• Assay: ≥90% (HPLC)
• Form: solid
• Storage condition: OK to freeze

Właściwości

• Nazwa produktu: Octan p-aminofenylomocznika, An organomercurial agent used for the activation of latent MMPs in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.
• Quality Segment: 100
• description: RTECS - OV5550000
• assay: ≥90% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: yellow
• solubility: 0.1 M NaOH: 10 mg/mL, DMSO: 10 mg/mL
• shipped in: ambient
• storage temp.: 10-30°C
• SMILES string: [Hg+]c1ccc(cc1)N.[O-]C(=O)C
• InChI: 1S/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1
• InChI key: RXSUFCOOZSGWSW-UHFFFAOYSA-M

Opis

General description

An organomercurial agent used for the activation of latent matrix metalloproteinases (MMPs) in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Activation of latent MMPs in vitro

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.

Other Notes

Chen, J.-M., et al. 1991. J. Biol. Chem. 266, 5113.
Marcy, A.I., et al. 1991. Biochemistry30, 6476.
Stricklin, G.P., et al. 1983. Biochemistry22, 61.

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Dla klientów z USA: Zawiera rtęć; Nie wyrzucać do śmieci - utylizować zgodnie z lokalnymi, stanowymi lub federalnymi przepisami.

Toxicity: Highly Toxic (H)

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• pictograms: GHS06,GHS08,GHS09
• signalword: Danger
• hcodes: H300 + H310 + H330,H373,H410
• pcodes: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
• Klasa składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable