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12-533

GSM (peptyd substratowy GSK3)

Name: GSM (peptyd substratowy GSK3)
Brand: MM
Price: 1270 PLN
Availability: InStock

Synonim(y):

Peptyd GSM, Peptyd substratu GSK3, Substrat dla GSK3

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Do Państwa/SKU	Dostępność	Cena netto
1 mg	Przewidywana wysyłka DZISIAJzKuehne + Nagel Sp. z o.o.	1270,00 zł

Informacje o tej pozycji

NACRES:

NA.41

UNSPSC Code:

12352200

eCl@ss:

32160405

1270,00 zł

Przewidywana wysyłka DZISIAJSzczegóły

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Właściwości

mol wt

M_w 2673 Da

Quality Segment

100

manufacturer/tradename

Upstate^®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

NM_019884.2

UniProt accession no.

P49840

shipped in

dry ice

Opis

Application

GSM (GSK3 substrate peptide) has been used:

in in vitro glycogen synthase kinase 3 (GSK-3)-3β activity assay to measure the kinase activity of GSK-3[1]
as a supplement in perfusates in kinase activity assay to determine the effect of the phosphatase-activating domain (PAD) peptide on squid axoplasm[2]
as a control in Kinase-Glo luminescent kinase assay to measure the influence of ibuprofen treatment on the catalytic activity of the kinase GSK3β[3]

Biochem/physiol Actions

Glycogen synthase kinase 3 (GSK3) is a protein kinase, which regulates glycogen metabolism. It regulates various cell functions, like signaling by insulin, growth factors and nutrients, and the specification of cell fates during embryonic development. GSK3 is involved modulating in apoptosis, cell division, and microtubule function.[4]

Physical form

1 mg of GSM lyophilized from 1 mL sterile, distilled water. Lyophilized powder.

Preparation Note

Lyophilized: 2 years at -20°C. Rehydrated: 6 months at -20°C

Analysis Note

Routinely evaluated as a substrate for GSK3β (Catalog # 14-306).

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Ta pozycja	12-340	12-373	12-123
Sigma-Aldrich 12-533 GSM (peptyd substratowy GSK3)	Sigma-Aldrich 12-340 Peptyd substratu Akt/SGK	Sigma-Aldrich 12-373 CHKtide (peptyd substratowy CHK1/CHK2)	Sigma-Aldrich 12-123 Peptyd substratu PKC
technique(s) activity assay: suitable (kinase)	technique(s) activity assay: suitable (kinase)	technique(s) activity assay: suitable (kinase)	technique(s) activity assay: suitable (kinase)
Quality Level 100	Quality Level 100	Quality Level 300	Quality Level 100
mol wt M_w 2673 Da	mol wt -	mol wt -	mol wt -
UniProt accession no. P49840	UniProt accession no. P31749	UniProt accession no. O14757, O96017	UniProt accession no. P17252
shipped in dry ice	shipped in dry ice	shipped in wet ice	shipped in wet ice
NCBI accession no. NM_019884.2	NCBI accession no. NM_001014431.1, NM_001014432.1, NM_005163.2	NCBI accession no. NM_001274.3	NCBI accession no. NM_002737.2

Klasa składowania

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c