1.06323

Sodium hydrogen carbonate

EMPROVE^® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, FCC, E 500

• Synonim(y): Sodium bicarbonate
• Wzór liniowy: NaHCO₃
• Numer CAS: 144-55-8
• Masa cząsteczkowa: 84.01
• Beilstein: 4153970
• Numer MDL: MFCD00003528
• Kod UNSPSC: 12352302
• Numer E: E500
• Numer indeksu EC: 205-633-8

Właściwości

• agency: BP; ChP; JP; Ph. Eur.; USP
• Poziom jakości: 500
• zgodność regionalna: FCC
• linia produktu: EMPROVE^® ESSENTIAL
• Formularz: solid
• pH: 8.6 (20 °C, 50 g/L in H₂O)
• pKa (25°C): (1) 6.37, (2) 10.25 (carbonic acid)
• mp: 270 °C (decomposition)
• rozpuszczalność: 96 g/L
• gęstość: 2.22 g/cm³ at 20 °C; 2.16 g/mL at 25 °C (lit.)
• Zastosowanie: liquid formulation; ophthalmics; pharmaceutical; solid formulation
• temp. przechowywania: 2-30°C
• ciąg SMILES: [Na+].OC([O-])=O
• InChI: 1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
• Klucz InChI: UIIMBOGNXHQVGW-UHFFFAOYSA-M

Opis

Opis ogólny

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Zastosowanie

Sodium hydrogen carbonate is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, sodium hydrogen carbonate is used as pH adjuster, or a source of carbon dioxide in oral formulations such as effervescent tablets or granules.

Informacje prawne

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable