07-1800
Anti-eIF4G Antibody
serum, from rabbit
Synonim(y):
eIF-4-gamma 1, eIF-4G 1, eukaryotic translation initiation factor 4 gamma 1
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About This Item
Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
pochodzenie biologiczne
rabbit
Poziom jakości
forma przeciwciała
serum
rodzaj przeciwciała
primary antibodies
klon
polyclonal
reaktywność gatunkowa
human, mouse
metody
immunofluorescence: suitable
western blot: suitable
numer dostępu NCBI
numer dostępu UniProt
Warunki transportu
wet ice
docelowa modyfikacja potranslacyjna
unmodified
informacje o genach
human ... EIF4G1(1981)
Opis ogólny
eIF4F is a translation initiation factor containing three subunits: eIF4A, eIF4E, and eIF4G. This complex is a key component in promoting ribosomal binding to the mRNA. eIF4G interacts with both eIF4A and eIF4E though its carboxy and amino terminal domains, respectively. eIF4E binds to the cap structure of the mRNA, while the ATP-dependent RNA helicase eIF4A unwinds the secondary structure of the 5’ UTR. eIF4G plays a critical role in coordinating the assembly of the eukaryotic initiation factors. It acts as a bridge to bind the cap-bound eIF4E, eIF4AI&II, the eIF3 complex, PABP1, and the kinase Mnk1 (Lejeune, F., et al., 2004) in a large eukaryotic initiation factor complex
Specyficzność
Not tested on other species.
This antibody detects eIF4G at its N-terminal region.
Immunogen
Epitope: N-terminus
Synthetic peptide corresponding to N-terminal region of human eIF4G.
Zastosowanie
Anti-eIF4G Antibody is an antibody against eIF4G for use in WB & IF.
Research Category
Signaling
Signaling
Research Sub Category
RNA Binding Protein (RBP)
Insulin/Energy Signaling
RNA Binding Protein (RBP)
Insulin/Energy Signaling
Jakość
Evaluated by western blot on HeLa cytoplasmic extract.
Western Blot Analysis: 1:1,000 dilution of this antibody was used to detect eIF4G in HeLa cytoplasmic extract and lysates from 293T and S10 cells.
Western Blot Analysis: 1:1,000 dilution of this antibody was used to detect eIF4G in HeLa cytoplasmic extract and lysates from 293T and S10 cells.
Opis wartości docelowych
220 kDa
Postać fizyczna
Rabbit polyclonal serum with 0.05% NaN3.
Przechowywanie i stabilność
Stable for 1 year at -20ºC from date of receipt.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
10 - Combustible liquids
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