N-078

(S)-N-Nitrosoanatabine solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonim(y): NAT
• Wzór empiryczny (zapis Hilla): C₁₀H₁₁N₃O
• Numer CAS: 71267-22-6
• Masa cząsteczkowa: 189.21
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material
• Postać: liquid
• Właściwości: (Snap-N-Spike^®)
• opakowanie: ampule of 1 mL
• producent / nazwa handlowa: Cerilliant^®
• stężenie: 1.0 mg/mL in acetonitrile
• metody: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Zastosowanie: forensics and toxicology
• format: single component solution
• temp. przechowywania: −20°C
• InChI: 1S/C10H11N3O/c14-12-13-7-2-1-5-10(13)9-4-3-6-11-8-9/h1-4,6,8,10H,5,7H2/t10-/m0/s1
• Klucz InChI: ZJOFAFWTOKDIFH-JTQLQIEISA-N

Opis

Opis ogólny

N-Nitrosoanatabine or NAT is a potent carcinogen and biomarker of exposure to cigarette smoke. It′s found in a variety of tobacco products such as cigarettes, electronic cigarettes, nicotine gum and oral snuff. This certified Snap-N-Spike^® solution is suitable for use in LC-MS/MS or GC/MS methods for nicotine testing, environmental monitoring, or clinical and diagnostic testing of nicotine biomarkers.

Zastosowanie

• (S)-N-Nitrosoanatabine solution in Cytochrome P450 Inhibition Studies: Utilizing (S)-N-Nitrosoanatabine solution, researchers have elucidated its role in the inhibition of the cytochrome P450 2A13 enzyme, critical for understanding nicotine metabolism pathways and developing strategies to mitigate tobacco-related cancers. This study highlights the solution′s utility in biochemical research and pharmacological studies, serving as a critical analytical standard for assessing the metabolic pathways of tobacco alkaloid derivatives (Liu et al., 2016).

Informacje prawne

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS07
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H225,H302 + H312 + H332,H319
• Zwroty wskazujące środki ostrożności: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Kod klasy składowania: 3 - Flammable liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): 35.6 °F - closed cup
• Temperatura zapłonu (°C): 2.0 °C - closed cup