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N-031

Supelco

Norfentanyl oxalate solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Wzór empiryczny (zapis Hilla):
C14H20N2O · C2H2O4
Numer CAS:
1211527-24-0
Masa cząsteczkowa:
322.36
Numer WE:
200-659-6
Numer MDL:
MFCD08272799
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329818426
NACRES:
NA.24
Informacje o cenach i dostępności nie są obecnie dostępne.

klasa czystości

certified reference material

Poziom jakości

300

Formularz

liquid

Właściwości

Snap-N-Spike®/Snap-N-Shoot®

opakowanie

ampule of 1 mL

producent / nazwa handlowa

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland)

stężenie

1.0 mg/mL in methanol (as free base)

metody

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Zastosowanie

forensics and toxicology

Format

single component solution

temp. przechowywania

−20°C

ciąg SMILES

OC(=O)C(O)=O.CCC(=O)N(C1CCNCC1)c2ccccc2

InChI

1S/C14H20N2O.C2H2O4/c1-2-14(17)16(12-6-4-3-5-7-12)13-8-10-15-11-9-13;3-1(4)2(5)6/h3-7,13,15H,2,8-11H2,1H3;(H,3,4)(H,5,6)

Klucz InChI

OLFNESLXXQCODF-UHFFFAOYSA-N

Powiązane kategorie

Opis ogólny

Norfentanyl is a major urinary metabolite of fentanyl, a potent synthetic analgesic sold under various trade names including Sublimaze, Duragesic®, Actiq®, and Fentora®. This Certified Spiking Solution® is suitable for numerous GC/MS or LC/MS testing applications from clinical toxicology and forensic analysis to urine drug testing and pain prescription monitoring.

Informacje prawne

Actiq is a registered trademark of Anesta Corp.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Duragesic is a registered trademark of Johnson & Johnson
Fentora is a registered trademark of Cima Labs, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
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Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H225,H301 + H311 + H331,H334,H370

Klasyfikacja zagrożeń

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Resp. Sens. 1 - STOT SE 1

Organy docelowe

Eyes,Central nervous system

Kod klasy składowania

3 - Flammable liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

49.5 °F - closed cup

Temperatura zapłonu (°C)

9.7 °C - closed cup

Wykazy regulacyjne

Wykazy regulacyjne dotyczą głównie produktów chemicznych. Można w nich podawać ograniczoną liczbę informacji na temat produktów niechemicznych. Brak wpisu oznacza, że żaden ze składników nie znajduje się w wykazie. Użytkownik odpowiada za zagwarantowanie bezpiecznego i zgodnego z prawem stosowania produktu.

EU REACH Annex XVII (Restriction List)

CAS No.

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number

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Fentanyl solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

F-002

Fentanyl solution

Vera Coopman et al.
Forensic science international, 169(2-3), 223-227 (2006-05-03)
Fentanyl is a potent synthetic narcotic analgesic administered in the form of a transdermal patch for the management of chronic pain. A 78-year-old woman with a history of cancer was found dead in bed. She was lying on her back.
D E Feierman et al.
Drug metabolism and disposition: the biological fate of chemicals, 24(9), 932-939 (1996-09-01)
The microsomal metabolism of fentanyl, a synthetic opioid commonly used in anesthesia, was investigated in human liver. Incubation of fentanyl with human hepatic microsomes fortified with NADPH resulted in the formation of a single major metabolite, namely norfentanyl, as determined
A K Valaer et al.
Journal of chromatographic science, 35(10), 461-466 (1997-10-23)
A sensitive, specific urinary assay for fentanyl, sufentanil, and alfentanil based on their N-dealkylated metabolites is described. Norfentanyl, norsufentanil-noralfentanil, and 2H5-norfentanyl are synthesized and characterized by standard analytical techniques. Derivatization of these secondary amines to yield the pentafluorobenzamides produces stable
Henry J Carson et al.
Legal medicine (Tokyo, Japan), 12(3), 157-159 (2010-04-07)
We recently encountered a subject who died from an uncommon misuse of a fentanyl transdermal patch, chewing, followed by complications of aspiration of the patch. We report this case to alert medical examiners to the troubling trend of increased fentanyl
Ming Jin et al.
Journal of analytical toxicology, 29(7), 590-598 (2006-01-20)
Pharmacogenomics, the study on genetic contributions to drug action may help in certifying fentanyl toxicity. Fentanyl is used clinically as an adjunct to surgical anesthesia and for chronic pain management. Its toxicity may be partially due to cytochrome P450 (CYP)
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Questions

  1. I'm interested in Fentanyl abuse test using urine specimen. Would this product work as positive control for this diagnostic test?

    1 answer

    1. Norfentanyl is a major urinary metabolite of fentanyl, a potent synthetic analgesic sold under various trade names including Sublimaze, Duragesic®, Actiq®, and Fentora®. Therefore, this Certified Spiking Solution is suitable for testing applications from clinical toxicology and forensic analysis to urine drug testing. So it can be used as a positive control for urinal drug testing.

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