M-105
Methyl-D3-malonic acid solution
1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
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About This Item
Wzór empiryczny (zapis Hilla):
C4H3O4D3
Numer CAS:
Masa cząsteczkowa:
121.11
Numer WE:
Kod UNSPSC:
41116107
NACRES:
NA.24
Polecane produkty
klasa czystości
certified reference material
Postać
liquid
Właściwości
Snap-N-Spike®/Snap-N-Shoot®
opakowanie
ampule of 1 mL
producent / nazwa handlowa
Cerilliant®
stężenie
1.0 mg/mL in acetonitrile
metody
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
Zastosowanie
clinical testing
pharmaceutical (small molecule)
format
single component solution
temp. przechowywania
−20°C
ciąg SMILES
[2H]C([2H])([2H])C(C(O)=O)C(O)=O
InChI
1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)/i1D3
Klucz InChI
ZIYVHBGGAOATLY-FIBGUPNXSA-N
Opis ogólny
Methylmalonic acid, a malonic acid derivative, is a vital intermediate in the metabolism of fat and proteins and plays a key role in energy metabolism. Elevated methylmalonic acid levels can be caused by an inborn error of metabolism leading to methylmalonic aciduria or indicate early vitamin B<sub>12</sub> deficiency. This internal standard is suitable for quantitation of methylmalonic acid levels by LC/MS or GC/MS in newborn screening and clinical testing applications to test for methylmalonic acidemia and diagnose vitamin B<sub>12</sub> deficiency.
Zastosowanie
- Assessment of Vitamin B-12 Status: Methyl-D3-malonic acid, as a deuterated derivative of malonic acid, was highlighted for its application in quantifying vitamin B-12 status using dried blood spots. This method provides a stable, precise measure and is useful in nutritional research and clinical diagnostics (Schroder et al., 2014).
- Improvement of Analytical Methods: Methyl-D3-malonic acid was used in a gas chromatography-mass spectrometry (GC-MS) technique to quantify methylmalonic acid in serum. This application underlines its role in improving diagnostic assays by offering enhanced precision and reliability in biochemical measurements (Straczek et al., 1993).
Informacje prawne
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
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produkt powiązany
Numer produktu
Opis
Cennik
Hasło ostrzegawcze
Danger
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
Kod klasy składowania
3 - Flammable liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Temperatura zapłonu (°F)
35.6 °F - closed cup
Temperatura zapłonu (°C)
2 °C - closed cup
Certyfikaty analizy (CoA)
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